Lens differentiation and crystallin regulation: a chick model
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چکیده
منابع مشابه
Lens differentiation and crystallin regulation: a chick model.
The vertebrate lens is a transparent polarized tissue that acts as the gateway for vision. The chick lens is an excellent model for studying tissue organogenesis, since it is both accessible and easily manipulated during embryonic stages. The chick lens consists of two morphologically discrete compartments, the epithelium and the fiber-cell mass. Evidence indicates that the early phases of lens...
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Cooperative action between L-Maf and Sox2 on δ-crystallin gene expression during chick lens development
Lens development is regulated by a variety of transcription factors with distinct properties. The lens-specific transcription factor, L-Maf, is essential for lens formation and induces lens-specific markers, such as the crystallin genes. In this study, we analyzed the mechanism by which L-Maf regulates delta-crystallin expression. Misexpression of L-Maf in the head ectoderm of lens placode-form...
متن کاملIsolation and in vitro translation of delta-crystallin mRNA from embryonic chick lens fibers.
Of the protein synthesized and accumulated during differentiation of embryonic chick lens fibers, 70-80% is the tissue specific protein delta-crystallin. We have isolated and partially characterized the total cytoplasmic mRNA from purified lens fibers of 15-day-old embryos as an initial step toward understanding the regulated expression of delta-crystallin during development. Each lens fiber ma...
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ژورنال
عنوان ژورنال: The International Journal of Developmental Biology
سال: 2004
ISSN: 0214-6282
DOI: 10.1387/ijdb.041863hr